| 论文题目 | A high-quality chromosomal genome assembly of the sea cucumber Chiridota heheva and its hydrothermal adaptation |
| 论文题目（英文） | A high-quality chromosomal genome assembly of the sea cucumber Chiridota heheva and its hydrothermal adaptation |
| 作者 | Yujin Pu(1,2);Yang Zhou(1);Jun Liu(1);Haibin Zhang(1) |
| 发表年度 | 2024-01 |
| 卷 | 13 |
| 期 | 1 |
| 页码 | 1–12 |
| 期刊名称 | GIGASCIENCE |
| 摘要 | Background: Chiridota heheva is a cosmopolitan holothurian well adapted to diverse deep-sea ecosystems, especially chemosynthetic environments. Besides high hydrostatic pressure and limited light, high concentrations of metal ions also represent harsh conditions in hydrothermal environments. Few holothurian species can live in such extreme conditions. Therefore, it is valuable to elucidate the adaptive genetic mechanisms of C. heheva in hydrothermal environments. Findings: Herein, we report a high-quality reference genome assembly of C. heheva from the Kairei vent, which is the first chromosome? level genome of Apodida. The chromosome-level genome size was 1.43 Gb, with a scaffold N50 of 53.24 Mb and BUSCO completeness score of 94.5%. Contig sequences were clustered, ordered, and assembled into 19 natural chromosomes. Comparative genome analysis found that the expanded gene families and positively selected genes of C. heheva were involved in the DNA damage repair process. The expanded gene families and the unique genes contributed to maintaining iron homeostasis in an iron-enriched environment. The positively selected gene RFC2 with 10 positively selected sites played an essential role in DNA repair under extreme environments. Conclusions: This first chromosome-level genome assembly of C. heheva reveals the hydrothermal adaptation of holothurians. As the first chromosome-level genome of order Apodida, this genome will provide the resource for investigating the evolution of class Holothuroidea. |
| 摘要_英文 |
Copyright？中国科学院深海科学与工程研究所 备案证号：琼ICP备13001552号-1
琼公网安备 46020102000014号
地址: 三亚市鹿回头路28号 邮编：572000 网站维护：深海所办公室 邮箱：office@idsse.ac.cn
